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fluocortolone

Structure via PubChem · Public domain (PubChem)

EntityQ5462793· pop 11· linked from 299 articles

fluocortolone

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Also known as SH-742

Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids.

Chemical data

Formula: C22H29FO4
Molecular weight: 376.5 g/mol
IUPAC name: (6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
Indications: hemorrhoid

via ChEMBL · EBI

Research

382 papers

Fluocortolone.2006
Fluocortolone.The British journal of dermatology · 1967
Pharmacokinetics of fluocortolone in man.European journal of clinical pharmacology · 1986
Fluocortolone: pharmacokinetics and effect on plasma cortisol level.European journal of clinical pharmacology · 1986
Fluocortolone: pharmacokinetics and effect on ACTH and cortisol secretion during daily and alternate-day administration.European journal of clinical pharmacology · 1988

Wikidata facts

Mass: 376.205

Show 5 more facts

chemical formula: C₂₂H₂₉FO₄
canonical SMILES: CC1CC2C3CC(C4=CC(=O)C=CC4(C3C(CC2(C1C(=O)CO)C)O)C)F
isomeric SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@H]1C(=O)CO)C)O)C)F
defined daily dose: 10
Commons category: Fluocortolone

Sources (3)

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Article

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Contents

See also
References

Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids.

It is similar to fluocortin, but with one less carbonyl group.

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Categories

Drugboxes which contain changes to verified fields Drugs with no legal status ECHA InfoCard ID from Wikidata Glucocorticoids Organofluorides