Structure via PubChem · Public domain (PubChem)
flutamid
Sign in to saveAlso known as alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-m-propionotoluidide, 4'-nitro-3'-trifluoromethylisobutyranilide, FTA, NFBA, niftolide
kimyasal bileşik
Key facts
- Drug.ChEMBL
- 806
- Drug.ChEBI
- 5132
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 461102563
- Drug.IUPAC_name
- 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
- Drug.image
- Flutamide.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 225
- Drug.image2
- Flutamide molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 225
- Drug.tradename
- Eulexin, others
- Drug.MedlinePlus
- a697045
- Drug.pregnancy_category
- D
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- By mouth
- Drug.class
- Nonsteroidal antiandrogen
- Drug.bioavailability
- Complete (>90%)
via Wikipedia infobox
Chemical data
- Formula
- C11H11F3N2O3
- Molecular weight
- 276.21 g/mol
- IUPAC name
- 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
- SMILES
- CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F
- InChIKey
- MKXKFYHWDHIYRV-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 74.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1989
- Admin. routes
- oral
- Indications
- prostate carcinoma, polycystic ovary syndrome, neoplasm, prostate adenocarcinoma
via ChEMBL · EBI
Research
4,021 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 276.072177
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₁H₁₁F₃N₂O₃
- canonical SMILES
- CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F
- defined daily dose
- 0.75
- Commons category
- Flutamide
- MCN code
- 2924.29.62
- physically interacts with
- androgen receptor
- legal status (medicine)
- boxed warning
Sources (9)
via Wikidata · CC0