GJB7

Also known as CX25, bA136M9.1, connexin25, gap junction protein beta 7

Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.

In the Vinony graph

Within Vinony's link graph, GJB7 is referenced by 300 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.

Vinony files it under Connexins and Genes on human chromosome 6.

Its subject is documented across 5 Wikipedia language editions.

Gene data

GJB7

Name: gap junction protein beta 7
Type: protein-coding
Position: 87,282,980–87,329,278 (−)
Aliases: CX25, bA136M9.1, connexin25
Ensembl: ENSG00000164411
RefSeq RNA: NM_198568.3
RefSeq protein: NP_940970.1

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008].

Gene Ontology

Biological process

cell communication cell-cell signaling transmembrane transport

Molecular function

gap junction channel activity gap junction channel activity

Cellular component

plasma membrane gap junction connexin complex connexin complex

Pathways

Gap junction trafficking and regulation Gap junction trafficking Gap junction assembly Membrane Trafficking Vesicle-mediated transport

via MyGene.info

Gene · Ensembl

gap junction protein beta 7

Symbol: GJB7
Biotype: Protein coding
Organism: Homo sapiens
Location: 6:87,282,980-87,329,278
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 89311
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/375519
genomic end: 88038996
genomic start: 87282980
chromosome: human chromosome 6
cytogenetic location: 6q14.3-q15

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

2 sections

Contents

Function
References

Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.

== Function == Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.

Excerpted from Wikipedia’s “GJB7” article, available under the CC BY-SA 4.0 licence.