catenin
Sign in to saveAlso known as Catenins
thumb|350px|Interactions of structural proteins at a cadherin-based adherens junction. The exact means by which [[cadherins are linked to actin filaments is still under investigation.]]
Research
57,681 papers- p120-catenin in canonical Wnt signaling.Critical reviews in biochemistry and molecular biology · 2017
- Delta-catenin at the synaptic-adherens junction.Trends in cell biology · 2005
- Cadherin-catenin proteins in vertebrate development.Current opinion in cell biology · 2006
- The β-catenin C terminus links Wnt and sphingosine-1-phosphate signaling pathways to promote vascular remodeling and atherosclerosis.Science advances · 2024
- p120-Catenin: a novel regulator of innate immunity and inflammation.Critical reviews in immunology · 2012
via PubMed
~13 min read
Encyclopedic overview
8 sectionsContents
- Types
- Function
- Interaction with cadherins
- Clinical significance
- Recent clinical studies
- Catenins and cancer
- References
- External links
thumb|350px|Interactions of structural proteins at a cadherin-based adherens junction. The exact means by which [[cadherins are linked to actin filaments is still under investigation.]]
Catenins are a family of proteins found in complexes with cadherin cell adhesion molecules of animal cells. The first two catenins that were identified became known as α-catenin and β-catenin. α-Catenin can bind to β-catenin and can also bind filamentous actin (F-actin). β-Catenin binds directly to the cytoplasmic tail of classical cadherins. Additional catenins such as γ-catenin and δ-catenin have been identified. The name "catenin" was originally selected ('catena' means 'chain' in Latin) because it was suspected that catenins might link cadherins to the cytoskeleton.
Excerpted from Wikipedia’s “catenin” article, available under the CC BY-SA 4.0 licence.