GYPA
Sign in to saveAlso known as CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN
protein-coding gene in the species Homo sapiens
Gene data
GYPA- Name
- glycophorin A (MNS blood group)
- Type
- protein-coding
- Position
- 144,108,904–144,140,751 (−)
- Aliases
- CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2
- Ensembl
- ENSG00000170180
- RefSeq RNA
- NM_001308187.2, NM_001308190.2, NM_001438046.1, NM_001438625.1, NM_001438626.1
- RefSeq protein
- NP_001295116.1, NP_001295119.1, NP_001424975.1, NP_001425554.1, NP_001425555.1
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
glycophorin A (MNS blood group)
- Symbol
- GYPA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:144,108,904-144,140,751
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein GYPA PDB 1afo.png
Show 8 more facts
- HomoloGene ID
- 48076
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2993
- genomic end
- 144140751
- genomic start
- 145030457
- chromosome
- human chromosome 4
- cytogenetic location
- 4q31.21
- expressed in
- spleen
Sources (3)
via Wikidata · CC0