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GeneQ18047967· pop 6· linked from 3 articles

Also known as H2A/S, H2AFALii, H2AH, dJ86C11.1, histone cluster 1, H2ah, histone cluster 1 H2A family member h, HIST1H2AH, H2A clustered histone 12

Histone H2A type 1-H is a protein that in humans is encoded by the HIST1H2AH gene.

Gene data

H2AC12
Name
H2A clustered histone 12
Type
protein-coding
Aliases
H2A/S, H2AFALii, H2AH, HIST1H2AH, dJ86C11.1

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015].

via MyGene.info

Gene · Ensembl

H2A clustered histone 12

Symbol
H2AC12
Biotype
Protein coding
Organism
Homo sapiens
Location
6:27,147,106-27,147,562
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
119667
genomic start
27147106
genomic end
27147562
cytogenetic location
6p22.1
Sources (4)

via Wikidata · CC0

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Article

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Contents
  • References
  • Further reading

Histone H2A type 1-H is a protein that in humans is encoded by the HIST1H2AH gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.

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