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GeneQ18032832· pop 5· linked from 2 articles

Also known as H2A/l, H2AFL, dJ221C16.4, histone cluster 1, H2ac, histone cluster 1 H2A family member c, HIST1H2AC, H2A clustered histone 6

Histone H2A type 1-C is a protein that in humans is encoded by the HIST1H2AC gene.

Gene data

H2AC6
Name
H2A clustered histone 6
Type
protein-coding
Aliases
H2A/l, H2AFL, HIST1H2AC, dJ221C16.4

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015].

via MyGene.info

Wikidata facts

Show 5 more facts
HomoloGene ID
130459
genomic end
26139344
genomic start
26124373
cytogenetic location
6p22.2
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  • Cancer
  • References
  • Further reading

Histone H2A type 1-C is a protein that in humans is encoded by the HIST1H2AC gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes.

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