H2BC12

Also known as H2B/S, H2BFAiii, H2BFT, H2BK, histone cluster 1, H2bk, histone cluster 1 H2B family member k, H2B clustered histone 12, HIST1H2BK

Histone H2B type 1-K is a protein that in humans is encoded by the HIST1H2BK gene.

Gene data

H2BC12

Name: H2B clustered histone 12
Type: protein-coding
Aliases: H2B/S, H2BFAiii, H2BFT, H2BK, HIST1H2BK

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015].

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Wikidata facts

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exact match: identifiers.org/ncbigene/85236
cytogenetic location: 6p22.1
HomoloGene ID: 135980
genomic start: 27146361
genomic end: 27146855

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Histone H2B type 1-K is a protein that in humans is encoded by the HIST1H2BK gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family. This gene is found in the histone microcluster on chromosome 6p21.33.