H4C1
Sign in to saveAlso known as H4FA, histone cluster 1, H4a, histone cluster 1 H4 family member a, HIST1H4A, H4 clustered histone 1, H4C5, H4C4, H4C9
Histone H4 is a protein that in humans is encoded by the HIST1H4A gene.
Gene data
H4C1- Name
- H4 clustered histone 1
- Type
- protein-coding
- Aliases
- H4FA, HIST1H4A
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 134481
- exact match
- identifiers.org/ncbigene/8359
- genomic start
- 26021649
- genomic end
- 26022050
- cytogenetic location
- 6p22.2
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Histone H4 is a protein that in humans is encoded by the HIST1H4A gene.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.