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GeneQ18032860· pop 5· linked from 3 articles

Also known as H4FA, histone cluster 1, H4a, histone cluster 1 H4 family member a, HIST1H4A, H4 clustered histone 1, H4C5, H4C4, H4C9

Histone H4 is a protein that in humans is encoded by the HIST1H4A gene.

Gene data

H4C1
Name
H4 clustered histone 1
Type
protein-coding
Aliases
H4FA, HIST1H4A

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015].

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Wikidata facts

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HomoloGene ID
134481
genomic start
26021649
genomic end
26022050
cytogenetic location
6p22.2
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Histone H4 is a protein that in humans is encoded by the HIST1H4A gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

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