Structure via PubChem · Public domain (PubChem)
halazepam
Sign in to saveAlso known as Alapryl®, SCH-12041, Halazepamum, Halazépam
Halazepam is a benzodiazepine derivative that was marketed under the brand names Paxipam in the United States, Alapryl in Spain, and Pacinone in Portugal.
Chemical data
- Formula
- C17H12ClF3N2O
- Molecular weight
- 352.7 g/mol
- IUPAC name
- 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one
- SMILES
- C1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3)CC(F)(F)F
- InChIKey
- WYCLKVQLVUQKNZ-UHFFFAOYSA-N
- XLogP
- 4
- Polar surface area
- 32.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1981
- Admin. routes
- oral
- Indications
- anxiety
via ChEMBL · EBI
Research
61 papers- Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine.Pharmacotherapy · 1982
- Multiple-dose halazepam kinetics.Clinical pharmacology and therapeutics · 1984
- New benzodiazepines: temazepam, halazepam, alprazolam, and triazolam.Journal of clinical psychopharmacology · 1982
- Halazepam (Paxipam)--another benzodiazepine.The Medical letter on drugs and therapeutics · 1982
- Chronic administration of and dependence on halazepam, diazepam, and nordiazepam in the dog.Drug and alcohol dependence · 1991
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 352.059025
- Has use
- medication
Show 6 more facts
- defined daily dose
- 0.1
- chemical formula
- C₁₇H₁₂ClF₃N₂O
- Commons category
- Halazepam
- medical condition treated
- anxiety disorder
- canonical SMILES
- C1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3)CC(F)(F)F
- MCN code
- 2933.91.34
via Wikidata · CC0
~2 min read
Encyclopedic overview
8 sectionsContents
- Medical uses
- Adverse effects
- Pharmacokinetics and pharmacodynamics
- Regulatory Information
- Commercial production
- See also
- References
- External links
Halazepam is a benzodiazepine derivative that was marketed under the brand names Paxipam in the United States, Alapryl in Spain, and Pacinone in Portugal.
==Medical uses== Halazepam was used for the treatment of anxiety.
Excerpted from Wikipedia’s “halazepam” article, available under the CC BY-SA 4.0 licence.