Histonmetyltransferas

Also known as histone methylase, histone methyltransferases

class of enzymes

Research

21,642 papers

Histone methyltransferase and drug resistance in cancers.Journal of experimental & clinical cancer research : CR · 2020
Discovery of cysteine-targeting covalent histone methyltransferase inhibitors.European journal of medicinal chemistry · 2023
Use of histone methyltransferase inhibitors in cancer treatment: A systematic review.European journal of pharmacology · 2023
The Promise for Histone Methyltransferase Inhibitors for Epigenetic Therapy in Clinical Oncology: A Narrative Review.Advances in therapy · 2020
The transcription factor code: a beacon for histone methyltransferase docking.Trends in cell biology · 2021

via PubMed

Wikidata facts

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Article · Svenska

Histonmetyltransferaser eller HMT är en grupp histonmodifierande enzymer som katalyserar överförandet av metylgrupper från den prostetiska gruppen S-adenosylmetionin till sidokedjorna på lysin- och argininrester i histonproteiner. Beroende på metyleringsmönstret kan dessa modifikationer leda till antingen ökad eller minskad transkriptionstakt av de närliggande generna.

Abstract from DBpedia / Wikipedia · CC BY-SA