HMOX2
Sign in to saveAlso known as HO-2, heme oxygenase 2
Heme oxygenase 2 is an enzyme that in humans is encoded by the HMOX2 gene.
In the Vinony graph
Within Vinony's link graph, HMOX2 is referenced by 6 other articles, and connects out to PubMed, human chromosome 16 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 16.
Its subject is documented across 5 Wikipedia language editions.
Gene data
HMOX2- Name
- heme oxygenase 2
- Type
- protein-coding
- Position
- 4,474,246–4,510,663 (+)
- Aliases
- HO-2
- Ensembl
- ENSG00000103415
- RefSeq RNA
- NM_001127204.2, NM_001127205.2, NM_001127206.3, NM_001286267.2, NM_001286268.2
- RefSeq protein
- NP_001120676.1, NP_001120677.1, NP_001120678.1, NP_001273196.1, NP_001273197.1
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
heme oxygenase 2
- Symbol
- HMOX2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR16_3_CTG1:177,013-212,670
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein HMOX2 PDB 2q32.png
Show 8 more facts
- HomoloGene ID
- 1611
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3163
- chromosome
- human chromosome 16
- genomic start
- 4524691
- genomic end
- 4560348
- cytogenetic location
- 16p13.3
- expressed in
- body of stomach
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Heme oxygenase 2 is an enzyme that in humans is encoded by the HMOX2 gene.
== Function ==
Excerpted from Wikipedia’s “HMOX2” article, available under the CC BY-SA 4.0 licence.