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isopropamide
Sign in to saveIsopropamide (R79) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.
Chemical data
- Formula
- C23H33N2O+
- Molecular weight
- 353.5 g/mol
- IUPAC name
- (4-amino-4-oxo-3,3-diphenylbutyl)-methyl-di(propan-2-yl)azanium
- SMILES
- CC(C)[N+](C)(CCC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)N)C(C)C
- InChIKey
- JTPUMZTWMWIVPA-UHFFFAOYSA-O
- XLogP
- 4.3
- Polar surface area
- 43.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 1
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1957
- Admin. routes
- oral
- Indications
- gastrointestinal disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 353.259
- Has use
- medication
Show 4 more facts
- Commons category
- Isopropamide
- defined daily dose
- 10.0
- canonical SMILES
- CC(C)[N+](C)(CCC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)N)C(C)C
- chemical formula
- C₂₃H₃₃N₂O⁺
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Isopropamide (R79) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.
==References==
Excerpted from Wikipedia’s “isopropamide” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0