levalbuterol

Also known as Levosalbutamol, (-)-Salbutamol, (-)-Albuterol, (R)-albuterol, (R)-salbutamol, R-salbutamol

Levosalbutamol, also known as levalbuterol, is a β2-adrenergic receptor agonist used in the treatment of bronchospasm. Levosalbutamol is the (R)-(−)-enantiomer of its prototype drug salbutamol.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 458951329
Drug.image: Levosalbutamol.svg
Drug.image_class: skin-invert-image
Drug.width: 225
Drug.image2: (R)-Salbutamol ball-and-stick model.png
Drug.image_class2: bg-transparent
Drug.width2: 225
Drug.USAN: levalbuterol
Drug.tradename: Xopenex, others
Drug.MedlinePlus: a603025
Drug.DailyMedID: Levalbuterol
Drug.pregnancy_AU: A
Drug.routes_of_administration: By mouth, inhalation
Drug.ATC_prefix: None
Drug.legal_US: Rx-only
Drug.metabolism: Liver

via Wikipedia infobox

Chemical data

Formula: C13H21NO3
Molecular weight: 239.31 g/mol
IUPAC name: 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1999
Admin. routes: topical
Indications: chronic obstructive pulmonary disease, asthma

via ChEMBL · EBI

~4 min read

Encyclopedic overview

10 sections

Contents

Medical use
Comparison to salbutamol
Adverse effects
Pharmacology
Mechanism of action
Society and culture
Economics
Legal status
Names
References

Levosalbutamol, also known as levalbuterol, is a β2-adrenergic receptor agonist used in the treatment of bronchospasm. Levosalbutamol is the (R)-(−)-enantiomer of its prototype drug salbutamol.

== Medical use == Levosalbutamol is indicated for the treatment or prevention of bronchospasm in people aged four years of age and older with reversible obstructive airway disease.

Excerpted from Wikipedia’s “levalbuterol” article, available under the CC BY-SA 4.0 licence.

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