لوامیزول

Also known as Ergamisol®, R-12564, (S)-(-)-tetramisole, (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole, (-)-tetramisole, (S)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole, (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole, (S)-(-)-levamisole

Levamisole, sold under the brand name Ergamisol among others, is a medication used to treat parasitic worm infections, specifically ascariasis and hookworm infections. It is taken by mouth.

Key facts

Drug.image: Levamisole.svg
Drug.image_class: skin-invert-image
Drug.width: 180
Drug.alt: Skeletal formula of levamisole
Drug.image2: Levamisole molecule ball.png
Drug.image_class2: bg-transparent
Drug.alt2: Ball-and-stick model of the levamisole molecule
Drug.tradename: Ergamisol, others
Drug.MedlinePlus: a697011
Drug.DailyMedID: Levamisole
Drug.routes_of_administration: By mouth
Drug.ATC_prefix: P02
Drug.ATC_suffix: CE01
Drug.legal_status: Rx-only (RU)
Drug.metabolism: Liver
Drug.elimination_half life: 3–4 hours
Drug.excretion: Kidney (70%)
Drug.CAS_number: 14769-73-4

via Wikipedia infobox

Chemical data

Formula: C11H12N2S
Molecular weight: 204.29 g/mol
IUPAC name: (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
SMILES: C1CSC2=N[C@H](CN21)C3=CC=CC=C3
InChIKey: HLFSDGLLUJUHTE-SNVBAGLBSA-N
XLogP: 1.8
Polar surface area: 40.9 Å²
H-bond donors: 0
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Withdrawn

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1990
Admin. routes: oral
Indications: acne, Aplastic anemia, hepatocellular carcinoma, Helminthiasis

via ChEMBL · EBI

Wikidata facts

Mass: 204.072119
Has use: medication

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defined daily dose: 0.15
chemical formula: C₁₁H₁₂N₂S
canonical SMILES: C1CSC2=NC(CN21)C3=CC=CC=C3
World Health Organisation international non-proprietary name: levamisole
isomeric SMILES: C1CSC2=N[C@H](CN21)C3=CC=CC=C3
Commons category: Levamisole
subject has role: essential medicine
found in taxon: Penicillium

Sources (5)

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via Wikidata sitelinks · CC0