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لوودوپا

Structure via PubChem · Public domain (PubChem)

EntityQ300989· pop 41· linked from 2,478 articles

لوودوپا

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Also known as 3,4-dihydroxy-L-phenylalanine, Sinemet®, L-3,4-dihydroxyphenylalanine, 3-Hydroxy-L-tyrosine, β-(3,4-dihydroxyphenyl)-L-alanine, Levodopa, Levodopum, β-(3,4-dihydroxyphenyl)alanine

-DOPA, also known as -3,4-dihydroxyphenylalanine and used medically as levodopa, is made and used as part of the normal biology of some plants and animals, including humans. Humans, as well as a portion of the other animals that utilize -DOPA, make it via biosynthesis from the amino acid -tyrosine.

Chemical data

Formula
C9H11NO4
Molecular weight
197.19 g/mol
IUPAC name
(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
SMILES
C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O
InChIKey
WTDRDQBEARUVNC-LURJTMIESA-N
XLogP
-2.7
Polar surface area
104 Ų
H-bond donors
4
H-bond acceptors
5
Formal charge
0

via PubChem

Wikidata facts

Mass
197.069
Has use
medication
Show 10 more facts
chemical formula
C₉H₁₁NO₄
Commons category
Levodopa
medical condition treated
Parkinson's disease
canonical SMILES
C1=CC(=C(C=C1CC(C(=O)O)N)O)O
isomeric SMILES
C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O
found in taxon
broad bean
World Health Organisation international non-proprietary name
levodopa
defined daily dose
3.5
MCN code
3003.90.45
significant drug interaction
(−)-selegiline
Sources (10)

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Gallery (3)