levonordefrin
Sign in to saveCorbadrine, sold under the brand name Neo-Cobefrine and also known as levonordefrin and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States. It is usually used in a pre-mixed solution with local anesthetics, such as mepivacaine.
Chemical data
- Formula
- C9H13NO3
- Molecular weight
- 183.2 g/mol
- IUPAC name
- 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol
via PubChem
Article
7 sectionsContents
- Pharmacology
- Pharmacokinetics
- Chemistry
- Society and culture
- Names
- References
- External links
Corbadrine, sold under the brand name Neo-Cobefrine and also known as levonordefrin and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States. It is usually used in a pre-mixed solution with local anesthetics, such as mepivacaine.
The drug acts as a non-selective agonist of the α1-, α2-, and β-adrenergic receptors. It is said to have preferential activity at the α2-adrenergic receptor.