Structure via PubChem · Public domain (PubChem)
methoxamine
Sign in to saveAlso known as 2,5-dimethoxynorephedrine, Méthoxamédrine, Méthoxamine, Methoxaminum, Metoxamina, Pseudomethoxamine, Methoxamin
Methoxamine, sold under the brand names Vasoxine, Vasoxyl, and Vasylox among others, is a sympathomimetic medication used as an antihypotensive agent. It has mostly or entirely been discontinued.
Chemical data
- Formula
- C11H17NO3
- Molecular weight
- 211.26 g/mol
- IUPAC name
- 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
- SMILES
- CC(C(C1=C(C=CC(=C1)OC)OC)O)N
- InChIKey
- WJAJPNHVVFWKKL-UHFFFAOYSA-N
- XLogP
- 0.5
- Polar surface area
- 64.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- parenteral
- Indications
- cardiovascular disease, fecal incontinence, Urinary incontinence
via ChEMBL · EBI
Research
3,256 papers- Methoxamine-induced rhythmic activity in rabbit anococcygeus muscle.General pharmacology · 1993
- Myocardial function--1972.Anesthesia and analgesia · 1972
- Vasopressors.Dental digest · 1972
- Effects of prophylactic injection of methoxamine on pregnant women undergoing cesarean delivery using spinal anesthesia.Journal of biological regulators and homeostatic agents · 2020
- A randomised dose-response study of prophylactic Methoxamine infusion for preventing spinal-induced hypotension during Cesarean delivery.BMC anesthesiology · 2020
via PubMed
Wikidata facts
- Mass
- 211.120843
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₁H₁₇NO₃
- canonical SMILES
- CC(C(C1=C(C=CC(=C1)OC)OC)O)N
- defined daily dose
- 30
- Commons category
- Methoxamine
- found in taxon
- Lophophora williamsii
via Wikidata · CC0
~2 min read
Encyclopedic overview
9 sectionsContents
- Medical uses
- Pharmacology
- Chemistry
- History
- Society and culture
- Names
- Availability
- See also
- References
Methoxamine, sold under the brand names Vasoxine, Vasoxyl, and Vasylox among others, is a sympathomimetic medication used as an antihypotensive agent. It has mostly or entirely been discontinued.
The drug is an α1-adrenergic receptor agonist.
Excerpted from Wikipedia’s “methoxamine” article, available under the CC BY-SA 4.0 licence.
Available in 10 languages
via Wikidata sitelinks · CC0