loteprednol
Sign in to saveAlso known as chloromethyl (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate, 17a-hydroxy-11b-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid chloromethyl ester
Loteprednol (formulated as the ester loteprednol etabonate) is a topical corticosteroid used to treat inflammations of the eye. It is marketed by Bausch and Lomb as Lotemax and Loterex.
Wikidata facts
- Mass
- 394.154701644
Show 4 more facts
- chemical formula
- C₂₁H₂₇ClO₅
- isomeric SMILES
- C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)OCCl)O)CCC4=CC(=O)C=C[C@]34C)O
- Commons category
- Loteprednol
- canonical SMILES
- CC12CC(C3C(C1CCC2(C(=O)OCCl)O)CCC4=CC(=O)C=CC34C)O
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Encyclopedic overview
12 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Retrometabolic drug design
- Chemistry
- Chemical synthesis
- References
- Further reading
Loteprednol (formulated as the ester loteprednol etabonate) is a topical corticosteroid used to treat inflammations of the eye. It is marketed by Bausch and Lomb as Lotemax and Loterex.
It was patented in 1980 and approved for medical use in 1998. It is available as a generic medication.
Excerpted from Wikipedia’s “loteprednol” article, available under the CC BY-SA 4.0 licence.
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