lurtotecan
Sign in to saveLurtotecan is a semi-synthetic analog of camptothecin with antineoplastic activity. Liposomal lurtotecan was in clinical trials as a treatment for topotecan-resistant ovarian cancer, but was discontinued.
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Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Lurtotecan is a semi-synthetic analog of camptothecin with antineoplastic activity. Liposomal lurtotecan was in clinical trials as a treatment for topotecan-resistant ovarian cancer, but was discontinued.
==Synthesis== thumb|center|600px|class=skin-invert-image|Lurtotecan synthesis Heck reaction Mitsunobu reaction Potassium osmate Sharpless asymmetric dihydroxylation Swern oxidation
Excerpted from Wikipedia’s “lurtotecan” article, available under the CC BY-SA 4.0 licence.