Lurtotecan is a semi-synthetic analog of camptothecin with antineoplastic activity. Liposomal lurtotecan was in clinical trials as a treatment for topotecan-resistant ovarian cancer, but was discontinued.
Lurtotecan is a semi-synthetic analog of camptothecin with antineoplastic activity. Liposomal lurtotecan was in clinical trials as a treatment for topotecan-resistant ovarian cancer, but was discontinued.
==Synthesis== thumb|center|600px|class=skin-invert-image|Lurtotecan synthesis Heck reaction Mitsunobu reaction Potassium osmate Sharpless asymmetric dihydroxylation Swern oxidation
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).