Structure via PubChem · Public domain (PubChem)
mabuterol
Sign in to saveMabuterol is a selective β2 adrenoreceptor agonist.
Chemical data
- Formula
- C13H18ClF3N2O
- Molecular weight
- 310.74 g/mol
- IUPAC name
- 1-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol
- SMILES
- CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)C(F)(F)F)O
- InChIKey
- JSJCTEKTBOKRST-UHFFFAOYSA-N
- XLogP
- 2.5
- Polar surface area
- 58.3 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
78 papers- Development of mabuterol transdermal patch: Molecular mechanism study of ion-pair improving patch stability.International journal of pharmaceutics · 2023
- Toxicology of mabuterol.Arzneimittel-Forschung · 1984
- Inhibitory effect of mabuterol on proliferation of rat ASMCs induced by PDGF-BB via regulating [Ca(2+)]i and mitochondrial fission/fusion.Chemico-biological interactions · 2019
- Pharmacological studies of mabuterol, a new selective beta 2-stimulant. I: Bronchodilating effect.Arzneimittel-Forschung · 1984
- Beta-adrenoceptor blocking effects of a selective beta 2-agonist, mabuterol, on the isolated, blood-perfused right atrium of the dog.British journal of pharmacology · 1989
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 310.106
Show 4 more facts
- chemical formula
- C₁₃H₁₈ClF₃N₂O
- canonical SMILES
- CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)C(F)(F)F)O
- subject has role
- bronchodilator
- Commons category
- Mabuterol
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Mabuterol is a selective β2 adrenoreceptor agonist.
==Synthesis== thumb|center|700px|class=skin-invert-image|Mabuterol synthesis
Excerpted from Wikipedia’s “mabuterol” article, available under the CC BY-SA 4.0 licence.