MAPRE1

Name

microtubule associated protein RP/EB family member 1

Type

protein-coding

Position

32,819,769–32,856,294 (+)

Aliases

EB1

Ensembl

ENSG00000101367

RefSeq RNA

NM_012325.3, XM_011528696.3, XM_054323204.1

RefSeq protein

NP_036457.1, XP_011526998.1, XP_054179179.1

The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

microtubule associated protein RP/EB family member 1

Symbol

MAPRE1

Biotype

Protein coding

Organism

Homo sapiens

Location

20:32,819,769-32,856,294

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein MAPRE1 PDB 1pa7.png

via Wikidata · CC0