MAPRE1
Sign in to saveAlso known as EB1, microtubule associated protein RP/EB family member 1
Microtubule-associated protein RP/EB family member 1 is a protein that in humans is encoded by the MAPRE1 gene.
In the Vinony graph
Vinony's link graph records 279 inbound references to MAPRE1, and connects out to hair keratin, PubMed and human chromosome 20.
It is catalogued under the topic Genes on human chromosome 20.
Vinony links it to 5 Wikipedia language editions.
Gene data
MAPRE1- Name
- microtubule associated protein RP/EB family member 1
- Type
- protein-coding
- Position
- 32,819,769–32,856,294 (+)
- Aliases
- EB1
- Ensembl
- ENSG00000101367
- RefSeq RNA
- NM_012325.3, XM_011528696.3, XM_054323204.1
- RefSeq protein
- NP_036457.1, XP_011526998.1, XP_054179179.1
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
microtubule associated protein RP/EB family member 1
- Symbol
- MAPRE1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:32,819,769-32,856,294
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein MAPRE1 PDB 1pa7.png
Show 7 more facts
- HomoloGene ID
- 56129
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/22919
- genomic end
- 31438211
- genomic start
- 32819954
- chromosome
- human chromosome 20
- cytogenetic location
- 20q11.21
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Microtubule-associated protein RP/EB family member 1 is a protein that in humans is encoded by the MAPRE1 gene.
== Function ==
Excerpted from Wikipedia’s “MAPRE1” article, available under the CC BY-SA 4.0 licence.