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meclofenoxate

Structure via PubChem · Public domain (PubChem)

EntityQ421147· pop 14· linked from 1,085 articles

meclofenoxate

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Also known as centrophenoxine

Meclofenoxate (INN, BAN; brand name Lucidril, also known as centrophenoxine) is a cholinergic nootropic used as a dietary supplement. It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA).

Chemical data

Formula
C12H16ClNO3
Molecular weight
257.71 g/mol
IUPAC name
2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate
SMILES
CN(C)CCOC(=O)COC1=CC=C(C=C1)Cl
InChIKey
XZTYGFHCIAKPGJ-UHFFFAOYSA-N
XLogP
2.5
Polar surface area
38.8 Ų
H-bond donors
0
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
attention deficit hyperactivity disorder

via ChEMBL · EBI

Wikidata facts

Has part
carbon
Mass
257.082
Show 4 more facts
chemical formula
C₁₂H₁₆ClNO₃
canonical SMILES
CN(C)CCOC(=O)COC1=CC=C(C=C1)Cl
subject has role
nootropic
Commons category
Meclofenoxate
Sources (3)

via Wikidata · CC0

~2 min read

Encyclopedic overview

5 sections
Contents
  • Side effects
  • Research
  • Brand names
  • See also
  • References

Meclofenoxate (INN, BAN; brand name Lucidril, also known as centrophenoxine) is a cholinergic nootropic used as a dietary supplement. It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA).

In elderly patients, meclofenoxate has been shown to improve performance on certain memory tests. Meclofenoxate also increases cellular membrane phospholipids. It is sold in Japan and some European countries, such as Germany, Hungary, and Austria, as a prescription drug.

Excerpted from Wikipedia’s “meclofenoxate” article, available under the CC BY-SA 4.0 licence.