adafenoxate

Chemical data

Formula

C20H26ClNO3

Molecular weight

363.9 g/mol

IUPAC name

2-(1-adamantylamino)ethyl 2-(4-chlorophenoxy)acetate

SMILES

C1C2CC3CC1CC(C2)(C3)NCCOC(=O)COC4=CC=C(C=C4)Cl

InChIKey

PLSMXIQMWYSHIV-UHFFFAOYSA-N

XLogP

4.7

Polar surface area

47.6 Ų

H-bond donors

1

H-bond acceptors

4

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

via ChEMBL · EBI

• Adafenoxate abolishes the amnesia induced by neonatal 6-hydroxydopamine treatment in rats.Methods and findings in experimental and clinical pharmacology · 1993
• Changes in brain biogenic monoamines induced by the nootropic drugs adafenoxate and meclofenoxate and by citicholine (experiments on rats).General pharmacology · 1990
• Comparative studies on the effects of the nootropic drug adafenoxate and of the cerebral vasodilator flunarizine on arterial smooth muscles.Acta physiologica et pharmacologica Bulgarica · 1988
• Effect of adafenoxate on different rat brain structures monoamine oxidase activity in vitro.Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology · 1989
• Comparative studies on the effects of the nootropic drugs adafenoxate, meclofenoxate and piracetam, and of citicholine on scopolamine-impaired memory, exploratory behavior and physical capabilities (experiments on rats and mice).Acta physiologica et pharmacologica Bulgarica · 1988

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

363.16

via Wikidata · CC0