Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C28H31NO10
- Molecular weight
- 541.5 g/mol
- IUPAC name
- (1R,10R,12R,21R,22S,23R,24R)-23-(dimethylamino)-4,8,12,22,24-pentahydroxy-10-methoxy-1,12-dimethyl-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2,4,7(16),8,14,18-hexaene-6,17-dione
- SMILES
- C[C@@]1(C[C@H](C2=C(C3=C(C=C2C1)C(=O)C4=C5C(=CC(=C4C3=O)O)[C@@]6([C@@H]([C@H]([C@@H]([C@H](O5)O6)O)N(C)C)O)C)O)OC)O
- InChIKey
- LWYJUZBXGAFFLP-OCNCTQISSA-N
- XLogP
- 0.8
- Polar surface area
- 166 Ų
- H-bond donors
- 5
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
119 papers- Menogaril, an anthracycline compound with a novel mechanism of action: cellular pharmacology.Japanese journal of cancer research : Gann · 1990
- Pharmacokinetics and systemic bioavailability of menogaril, an anthracycline antitumor agent, in the mouse, dog, and monkey.Cancer research · 1989
- Menogaril: a new anthracycline agent entering clinical trials.Investigational new drugs · 1984
- Hepatocellular carcinoma. An ECOG randomized phase II study of beta-interferon and menogaril.American journal of clinical oncology · 1995
- The Uridylyl Transferase TUT7-Mediated Accumulation of Exosomal miR-1246 Reprograms TAMs to Support CRC Progression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 541.195
Show 3 more facts
- chemical formula
- C₂₈H₃₁NO₁₀
- isomeric SMILES
- C[C@]1(CC2=CC3=C(C(=C2[C@@H](C1)OC)O)C(=O)C4=C(C=C5C(=C4C3=O)O[C@H]6[C@H]([C@@H]([C@H]([C@@]5(O6)C)O)N(C)C)O)O)O
- canonical SMILES
- CC1(CC2=CC3=C(C(=C2C(C1)OC)O)C(=O)C4=C(C=C5C(=C4C3=O)OC6C(C(C(C5(O6)C)O)N(C)C)O)O)O
Sources (2)
via Wikidata · CC0