methacycline

Also known as GS-2876, 6-demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline, 6-deoxy-6-demethyl-6-methylene-5-oxytetracycline, 6-methylene-5-hydroxytetracycline, 6-methylene-5-oxytetracycline, 6-methyleneoxytetracycline, methylenecycline

Metacycline or methacycline is a tetracycline antibiotic. It is used as a precursor in the industrial synthesis of doxycycline hyclate.

Research

431 papers

Methacycline displays a strong efficacy in reducing toxicity in a SCA3 Caenorhabditis elegans model.Biochimica et biophysica acta. General subjects · 2019
Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines.The Journal of antimicrobial chemotherapy · 2006
The tetracyclines.The Medical clinics of North America · 1970
Tetracyclines.Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abt.: Allgemeine, landwirtschaftliche und technische Mikrobiologie · 1973
Inhibition of epithelial-to-mesenchymal transition and pulmonary fibrosis by methacycline.American journal of respiratory cell and molecular biology · 2014

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Wikidata facts

Mass: 442.1376

Show 6 more facts

chemical formula: C₂₂H₂₂N₂O₈
defined daily dose: 0.6
World Health Organisation international non-proprietary name: metacycline
isomeric SMILES: CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=CC=CC(=C4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O)O
canonical SMILES: CN(C)C1C2C(C3C(=C)C4=CC=CC(=C4C(=O)C3=C(C2(C(=O)C(=C1O)C(=O)N)O)O)O)O
Commons category: Metacycline

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