Structure via PubChem · Public domain (PubChem)
mirabegron
Sign in to saveAlso known as Betmiga®, Myrbetriq®, YM-178
Mirabegron, sold under the brand name Myrbetriq among others, is a medication used to treat overactive bladder. Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine. It is taken by mouth.
Chemical data
- Formula
- C21H24N4O2S
- Molecular weight
- 396.5 g/mol
- IUPAC name
- 2-(2-amino-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]acetamide
- SMILES
- C1=CC=C(C=C1)[C@H](CNCCC2=CC=C(C=C2)NC(=O)CC3=CSC(=N3)N)O
- InChIKey
- PBAPPPCECJKMCM-IBGZPJMESA-N
- XLogP
- 2.1
- Polar surface area
- 129 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
1,123 papers- Mirabegron: Pediatric First Approval.Paediatric drugs · 2021
- Mirabegron: The most promising adipose tissue beiging agent.Physiological reports · 2021
- Efficacy and safety of vibegron compared with mirabegron for overactive bladder: A systematic review and network meta-analysis.Lower urinary tract symptoms · 2023
- Mirabegron and Anticholinergics in the Treatment of Overactive Bladder Syndrome: A Meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
- Activation of β3-adrenergic receptor by mirabegron prevents aortic dissection/aneurysm by promoting lymphangiogenesis in perivascular adipose tissue.Cardiovascular research · 2024
via PubMed
Wikidata facts
- Mass
- 396.162
Show 6 more facts
- chemical formula
- C₂₁H₂₄N₄O₂S
- isomeric SMILES
- C1=CC=C(C=C1)[C@H](CNCCC2=CC=C(C=C2)NC(=O)CC3=CSC(=N3)N)O
- canonical SMILES
- C1=CC=C(C=C1)C(CNCCC2=CC=C(C=C2)NC(=O)CC3=CSC(=N3)N)O
- World Health Organisation international non-proprietary name
- mirabegron
- defined daily dose
- 50
- Commons category
- Mirabegron
Sources (7)
via Wikidata · CC0
~5 min read
Article
5 sectionsContents
- Medical uses
- Adverse effects
- Research
- References
- Further reading
{{Drugbox | image = Mirabegron.svg | image_class = skin-invert-image | width = 300 | alt =
| tradename = Myrbetriq, Betanis, Betmiga, others | Drugs.com = | MedlinePlus = a612038 | DailyMedID = Mirabegron | pregnancy_AU = B3 | pregnancy_category = | routes_of_administration = By mouth | ATC_prefix = G04 | ATC_suffix = BD12
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via Wikidata sitelinks · CC0