Ácido micofenólico
Also known as ERL080, ERL-080, (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
compuesto químico
Chemical data
- Formula
- C17H20O6
- Molecular weight
- 320.3 g/mol
- IUPAC name
- (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
- SMILES
- CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\C)/CCC(=O)O)O
- InChIKey
- HPNSFSBZBAHARI-RUDMXATFSA-N
- XLogP
- 3.2
- Polar surface area
- 93.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
10,995 papersArticle · Español
El ácido micofenólico o micofenolato es un medicamento inmunosupresor derivado del , y especies relacionadas. Bloquea la síntesis de novo de los nucleótidos de purina mediante la inhibición de la enzima inosina monofosfato deshidrogenasa. En la práctica médica las sustancias que se administran son micofenolato de sodio o micofenolato mofetilo (profármaco), las cuales liberan ácido micofenólico que es la sustancia activa.
Abstract from DBpedia / Wikipedia · CC BY-SA
Connections
Categories
Carboxylic acidsChemicals using indexlabelsDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs developed by GenentechDrugs developed by Hoffmann-La RocheDrugs developed by NovartisDrugs with non-standard legal statusECHA InfoCard ID from WikidataHydroxyarenesImmunosuppressantsInfobox drug with local INN variant