Structure via PubChem · Public domain (PubChem)
NAN 190
Sign in to saveAlso known as NAN-190, NAN190, 1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine
NAN-190 is a drug and research chemical widely used in scientific studies. It was previously believed to act as a selective 5-HT1A receptor antagonist, but a subsequent discovery showed that it also potently blocks the α2-adrenergic receptor. The new finding has raised significant concerns about studies using NAN-190 as a specific serotonin receptor antagonist.
Chemical data
- Formula
- C23H27N3O3
- Molecular weight
- 393.5 g/mol
- IUPAC name
- 2-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]isoindole-1,3-dione
- SMILES
- COC1=CC=CC=C1N2CCN(CC2)CCCCN3C(=O)C4=CC=CC=C4C3=O
- InChIKey
- SJDOMIRMMUGQQK-UHFFFAOYSA-N
- XLogP
- 3.2
- Polar surface area
- 53.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- heterocyclic compound
- Has part
- carbon
- Mass
- 393.205242
- Has use
- medication
Show 3 more facts
- chemical formula
- C₂₃H₂₇N₃O₃
- canonical SMILES
- COC1=CC=CC=C1N2CCN(CC2)CCCCN3C(=O)C4=CC=CC=C4C3=O
- Commons category
- NAN-190
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
NAN-190 is a drug and research chemical widely used in scientific studies. It was previously believed to act as a selective 5-HT1A receptor antagonist, but a subsequent discovery showed that it also potently blocks the α2-adrenergic receptor. The new finding has raised significant concerns about studies using NAN-190 as a specific serotonin receptor antagonist.
==References==
Excerpted from Wikipedia’s “NAN 190” article, available under the CC BY-SA 4.0 licence.