Nitroxolina

Also known as A-82, 8-Hydroxy-5-nitroquinoline, 5-Nitro-8-quinolinol, 5-Nitro-8-oxyquinoline, 5-Nitrox, 5-NOK, 5NOK, 5-Nitro-8-hydroxyquinoline

composto chimico

Key facts

Drug.Verifiedfields: changed
Drug.verifiedrevid: 462262233
Drug.IUPAC_name: 5-nitro-quinolin-8-ol
Drug.image: Nitroxolin.svg
Drug.image_class: skin-invert-image
Drug.width: 120px
Drug.legal_US: IND
Drug.CAS_number: 4008-48-4
Drug.ATC_prefix: J01
Drug.ATC_suffix: XX07
Drug.PubChem: 19910
Drug.DrugBank: DB01422
Drug.ChemSpiderID: 18756
Drug.UNII: A8M33244M6
Drug.KEGG: D07245
Drug.ChEMBL: 1454910
Drug.C: 9
Drug.H: 6

via Wikipedia infobox

Research

230 papers

Nitroxoline: treatment and prevention of urinary tract infections from the urologist's perspective.Central European journal of urology · 2024
Nitroxoline: repurposing its antimicrobial to antitumor application.Acta biochimica Polonica · 2019
Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria.Nature communications · 2025
Rediscovering nitroxoline: a metal-chelating agent bridging infection and cancer.Drug discovery today · 2025
Nitroxoline is a novel inhibitor of NLRP3-dependent pyroptosis.Cell death discovery · 2025

via PubMed

Wikidata facts

Mass: 190.038

Show 5 more facts

chemical formula: C₉H₆N₂O₃
canonical SMILES: C1=CC2=C(C=CC(=C2N=C1)O)[N+](=O)[O-]
World Health Organisation international non-proprietary name: nitroxolinum
defined daily dose: 1
melting point: 180

Sources (6)

via Wikidata · CC0

Article · Italiano

Nitroxolina è un antibiotico, un agente chimicamente simile ai derivati ossochinolinici, dotato di proprietà antibatterica ed antifungina. Il farmaco è stato in uso in Europa per circa cinquant'anni, e ha dimostrato di essere molto efficace nel combattere le infezioni da biofilm. Il farmaco è stato utilizzato prevalentemente per il trattamento delle infezioni delle vie urinarie.

Abstract from DBpedia / Wikipedia · CC BY-SA