Structure via PubChem · Public domain (PubChem)
Nitroxolina
Sign in to saveAlso known as A-82, 8-Hydroxy-5-nitroquinoline, 5-Nitro-8-quinolinol, 5-Nitro-8-oxyquinoline, 5-Nitrox, 5-NOK, 5NOK, 5-Nitro-8-hydroxyquinoline
composto chimico
Key facts
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 462262233
- Drug.IUPAC_name
- 5-nitro-quinolin-8-ol
- Drug.image
- Nitroxolin.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 120px
- Drug.legal_US
- IND
- Drug.CAS_number
- 4008-48-4
- Drug.ATC_prefix
- J01
- Drug.ATC_suffix
- XX07
- Drug.PubChem
- 19910
- Drug.DrugBank
- DB01422
- Drug.ChemSpiderID
- 18756
- Drug.UNII
- A8M33244M6
- Drug.KEGG
- D07245
- Drug.ChEMBL
- 1454910
- Drug.C
- 9
- Drug.H
- 6
via Wikipedia infobox
Chemical data
- Formula
- C9H6N2O3
- Molecular weight
- 190.16 g/mol
- IUPAC name
- 5-nitroquinolin-8-ol
- SMILES
- C1=CC2=C(C=CC(=C2N=C1)O)[N+](=O)[O-]
- InChIKey
- RJIWZDNTCBHXAL-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 78.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- bacterial disease
via ChEMBL · EBI
Research
230 papers- Nitroxoline: treatment and prevention of urinary tract infections from the urologist's perspective.Central European journal of urology · 2024
- Nitroxoline: repurposing its antimicrobial to antitumor application.Acta biochimica Polonica · 2019
- Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria.Nature communications · 2025
- Rediscovering nitroxoline: a metal-chelating agent bridging infection and cancer.Drug discovery today · 2025
- Nitroxoline is a novel inhibitor of NLRP3-dependent pyroptosis.Cell death discovery · 2025
via PubMed
Wikidata facts
- Mass
- 190.038
- Has use
- medication
Show 8 more facts
- chemical formula
- C₉H₆N₂O₃
- route of administration
- oral administration
- canonical SMILES
- C1=CC2=C(C=CC(=C2N=C1)O)[N+](=O)[O-]
- World Health Organisation international non-proprietary name
- nitroxolinum
- defined daily dose
- 1
- subject has role
- antifungal
- medical condition treated
- urinary tract infection
- melting point
- 180
via Wikidata · CC0
Article · Italiano
Nitroxolina è un antibiotico, un agente chimicamente simile ai derivati ossochinolinici, dotato di proprietà antibatterica ed antifungina. Il farmaco è stato in uso in Europa per circa cinquant'anni, e ha dimostrato di essere molto efficace nel combattere le infezioni da biofilm. Il farmaco è stato utilizzato prevalentemente per il trattamento delle infezioni delle vie urinarie.
Abstract from DBpedia / Wikipedia · CC BY-SA