Structure via PubChem · Public domain (PubChem)
oxazepam
Sign in to saveAlso known as Serax®, WY-3498, (RS)-Oxazepam, (+-)-Oxazepam, Tazepam, Serax
Oxazepam is a short-to-intermediate-acting benzodiazepine. Oxazepam is used for the treatment of anxiety, insomnia, and to control symptoms of alcohol withdrawal syndrome.
Key facts
- Drug.ChEMBL
- 568
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- BA04
- Drug.CAS_number
- 604-75-1
- Drug.verifiedrevid
- 460765704
- Drug.class
- Benzodiazepine
- Drug.IUPAC_name
- (RS)-7-Chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
- Drug.image
- Oxazepam.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 190
- Drug.image2
- Oxazepam3d.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 150
- Drug.tradename
- Serax, Alepam, Serepax, others
- Drug.legal_AU
- S4
- Drug.legal_BR
- B1
- Drug.legal_CA
- Schedule IV
- Drug.legal_DE
- Rx-only/Anlage III
via Wikipedia infobox
Chemical data
- Formula
- C15H11ClN2O2
- Molecular weight
- 286.71 g/mol
- IUPAC name
- 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
- SMILES
- C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O
- InChIKey
- ADIMAYPTOBDMTL-UHFFFAOYSA-N
- XLogP
- 2.2
- Polar surface area
- 61.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
2,109 papers- Oxazepam.IARC monographs on the evaluation of carcinogenic risks to humans · 1996
- Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam.Journal of clinical pharmacy and therapeutics · 2001
- Oxazepam: update 1989.International clinical psychopharmacology · 1990
- Metabolic profile of oxazepam and related benzodiazepines: clinical and forensic aspects.Drug metabolism reviews · 2017
- The clinical pharmacology of oxazepam.Acta psychiatrica Scandinavica. Supplementum · 1978
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 286.051
- Has use
- medication
Show 8 more facts
- Commons category
- Oxazepam
- MCN code
- 2933.91.64
- chemical formula
- C₁₅H₁₁ClN₂O₂
- legal status (medicine)
- boxed warning
- medical condition treated
- anxiety disorder
- canonical SMILES
- C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O
- defined daily dose
- 50
- significant drug interaction
- loxapine
Sources (9)
via Wikidata · CC0
~11 min read
Encyclopedic overview
20 sectionsContents
- Medical uses
- Side effects
- Tolerance, dependence and withdrawal
- Contraindications
- Special precautions
- Pregnancy
- Interactions
- Overdose
- Pharmacology
- Chemistry
- Frequency of use
- Society and culture
- Misuse
- Legal status
- Brand names
- In popular culture
- Environmental concerns
- See also
- References
- External links
Oxazepam is a short-to-intermediate-acting benzodiazepine. Oxazepam is used for the treatment of anxiety, insomnia, and to control symptoms of alcohol withdrawal syndrome.
It is a metabolite of diazepam, prazepam, and temazepam, and has moderate amnesic, anxiolytic, anticonvulsant, hypnotic, sedative, and skeletal muscle relaxant properties compared to other benzodiazepines.
Excerpted from Wikipedia’s “oxazepam” article, available under the CC BY-SA 4.0 licence.