PARP2

Name

poly(ADP-ribose) polymerase 2

Type

protein-coding

Position

20,343,601–20,357,905 (+)

Aliases

ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2

Ensembl

ENSG00000291803

RefSeq RNA

NM_001042618.2, NM_005484.4, XM_005267247.4, XM_017020912.2, XM_047430869.1

RefSeq protein

NP_001036083.1, NP_005475.2, XP_005267304.1, XP_016876401.1, XP_047286825.1

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

poly(ADP-ribose) polymerase 2

Symbol

PARP2

Biotype

Protein coding

Organism

Homo sapiens

Location

14:20,343,541-20,362,074

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein PARP2 PDB 1gs0.png

via Wikidata · CC0