PARP3
Sign in to saveAlso known as ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1, PADPRT-3, poly(ADP-ribose) polymerase family member 3
Poly [ADP-ribose] polymerase 3 is an enzyme that in humans is encoded by the PARP3 gene.
Gene data
PARP3- Name
- poly(ADP-ribose) polymerase family member 3
- Type
- protein-coding
- Position
- 51,942,252–51,948,871 (+)
- Aliases
- ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1, PADPRT-3
- Ensembl
- ENSG00000041880
- RefSeq RNA
- NM_001003931.4, NM_001003935.2, NM_001370239.1, NM_001370240.1, NM_005485.6
- RefSeq protein
- NP_001003931.4, NP_001357168.1, NP_001357169.1, NP_005476.4, XP_047303043.1
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Wikidata facts
- Image
- Protein PARP3 PDB 2pa9.png
Show 6 more facts
- HomoloGene ID
- 4005
- exact match
- identifiers.org/ncbigene/10039
- genomic end
- 51982883
- genomic start
- 51976361
- cytogenetic location
- 3p21.2
- Commons category
- PARP3
Sources (4)
via Wikidata · CC0
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- Further reading
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Poly [ADP-ribose] polymerase 3 is an enzyme that in humans is encoded by the PARP3 gene.
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.