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pheniramine
Sign in to saveAlso known as SID90341510, Pheniraminum, Feniramina
Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine. Pheniramine is also commonly found in eyedrops used for the treatment of allergic conjunctivitis.
Chemical data
- Formula
- C16H20N2
- Molecular weight
- 240.34 g/mol
- IUPAC name
- N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine
- SMILES
- CN(C)CCC(C1=CC=CC=C1)C2=CC=CC=N2
- InChIKey
- IJHNSHDBIRRJRN-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 16.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
3,001 papers- Chlorpheniramine, an Old Drug with New Potential Clinical Applications: A Comprehensive Review of the Literature.Current reviews in clinical and experimental pharmacology · 2024
- Pheniramine dependence in obsessive-compulsive disorder: A case report.The International journal of risk & safety in medicine · 2022
- Assessment of pheniramine in alternative biological matrices by liquid chromatography tandem mass spectrometry.Forensic science, medicine, and pathology · 2024
- Effect of pheniramine maleate on rat skeletal muscle ischemia-reperfusion injury.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
- Pheniramine--a much abused drug.The Medical journal of Australia · 1994
via PubMed
~3 min read
Encyclopedic overview
6 sectionsContents
- Side effects
- Chemical relatives
- Stereoisomerism
- See also
- References
- External links
Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine. Pheniramine is also commonly found in eyedrops used for the treatment of allergic conjunctivitis.
It was patented in 1948. Pheniramine is generally sold in combination with other medications, rather than as a stand-alone drug, although some formulations are available containing pheniramine by itself.
Excerpted from Wikipedia’s “pheniramine” article, available under the CC BY-SA 4.0 licence.