sulthiame
Sign in to saveAlso known as Sultiame
Sultiame, or sulthiame, sold under the brand name Ospolot among others, is a sulfonamide and inhibitor of the enzyme carbonic anhydrase which is used as an anticonvulsant in the treatment of epilepsy. In addition to its use as an antiepileptic medication, recent studies showed promise in reducing sleep disordered breathing and other symptoms of obstructive sleep apnea (OSA).
Research
234 papers- Sulthiame add-on therapy for epilepsy.The Cochrane database of systematic reviews · 2019
- Sulthiame monotherapy for epilepsy.The Cochrane database of systematic reviews · 2021
- Sulthiame add-on therapy for epilepsy.The Cochrane database of systematic reviews · 2015
- Sulthiame add-on therapy for epilepsy.The Cochrane database of systematic reviews · 2013
- Sulthiame monotherapy for epilepsy.The Cochrane database of systematic reviews · 2014
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 290.039
Show 4 more facts
- chemical formula
- C₁₀H₁₄N₂O₄S₂
- canonical SMILES
- C1CCS(=O)(=O)N(C1)C2=CC=C(C=C2)S(=O)(=O)N
- subject has role
- anticonvulsant agent
- Commons category
- Sultiame
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Encyclopedic overview
12 sectionsContents
- Medical uses
- Adverse effects
- Overdose
- Interactions
- Chemistry
- Synthesis
- History
- Society and culture
- Availability
- Research
- See also
- References
Sultiame, or sulthiame, sold under the brand name Ospolot among others, is a sulfonamide and inhibitor of the enzyme carbonic anhydrase which is used as an anticonvulsant in the treatment of epilepsy. In addition to its use as an antiepileptic medication, recent studies showed promise in reducing sleep disordered breathing and other symptoms of obstructive sleep apnea (OSA).
==Medical uses== Historically, sultiame has been used to treat partial seizures. In Australia, it is currently registered for behavioural disorders associated with epilepsy; hyperkinetic behaviour; temporal lobe epilepsy; myoclonic seizures; grand mal attacks; and Jacksonian seizures. In contrast to other sulfonamide drugs, sultiame is devoid of antibacterial activity.
Excerpted from Wikipedia’s “sulthiame” article, available under the CC BY-SA 4.0 licence.
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