picotamide
Sign in to savePicotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor. Picotamide is licensed in Italy for the treatment of clinical arterial thrombosis and peripheral artery disease.
Research
117 papers- Picotamide inhibits a wide spectrum of agonist-induced smooth muscle contractions in porcine renal interlobar and coronary arteries.Pharmacology research & perspectives · 2021
- A review of picotamide in the reduction of cardiovascular events in diabetic patients.Vascular health and risk management · 2007
- Picotamide, a combined inhibitor of thromboxane A2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the DAVID study.European heart journal · 2004
- Mechanism of the persisting TxA2 receptor antagonism by picotamide.Thrombosis research · 1997
- Picotamide in migraine aura prevention: a pilot study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2004
via PubMed
Wikidata facts
- Mass
- 376.154
Show 2 more facts
- chemical formula
- C₂₁H₂₀N₄O₃
- canonical SMILES
- COC1=C(C=C(C=C1)C(=O)NCC2=CN=CC=C2)C(=O)NCC3=CN=CC=C3
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Picotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor. Picotamide is licensed in Italy for the treatment of clinical arterial thrombosis and peripheral artery disease.
== References ==
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via Wikidata sitelinks · CC0
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