胆色素原
Also known as 2-aminomethylpyrrol-3-acetic acid 4-propionic acid, 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid, PBG, 5-(Aminomethyl)-4-(carboxymethyl)-Pyrrole-3-propionic acid, 5-(Aminomethyl)-4-(carboxymethyl)-Pyrrole-3-propionate
Porphobilinogen (PBG) is an organic compound that occurs in living organisms as an intermediate in the biosynthesis of porphyrins, which include critical substances like hemoglobin and chlorophyll.
Chemical data
- Formula
- C10H14N2O4
- Molecular weight
- 226.23 g/mol
- IUPAC name
- 3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
- SMILES
- C1=C(C(=C(N1)CN)CC(=O)O)CCC(=O)O
- InChIKey
- QSHWIQZFGQKFMA-UHFFFAOYSA-N
- XLogP
- -3.5
- Polar surface area
- 116 Ų
- H-bond donors
- 4
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
3,963 papersArticle · 中文
胆色素原（英語：Porphobilinogen，亦称为卟胆原，简称为PBG）是一种作为卟啉(Porphyrin)生物合成中间体的吡咯(Pyrrole)衍生物，而卟啉(Porphyrin)為合成血基質的原料之一。 由两分子(下圖dALA) 在(又稱下圖之，圖上ALA dehydrogenase為誤植)催化下缩合、环化而成。而后4分子胆色素原在（下圖右側 PB deaminase）催化下，将脱去侧链上的氨基，缩聚为含有4个吡咯(Pyrrole)环的。(見下圖右側 Hydroxymethyl bilane) 在急性間歇性紫質症患者之尿液中，胆色素原會有增加的情況。 * 血紅素合成
Abstract from DBpedia / Wikipedia · CC BY-SA