PPIH
Sign in to saveAlso known as CYP-20, CYPH, SnuCyp-20, USA-CYP, peptidylprolyl isomerase H
Peptidyl-prolyl cis-trans isomerase H is an enzyme that in humans is encoded by the PPIH gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to PPIH, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 4 Wikipedia language editions.
Gene data
PPIH- Name
- peptidylprolyl isomerase H
- Type
- protein-coding
- Position
- 42,658,185–42,676,758 (+)
- Aliases
- CYP-20, CYPH, SnuCyp-20, USA-CYP
- Ensembl
- ENSG00000171960
- RefSeq RNA
- NM_001330510.2, NM_006347.4, XM_005270362.2, XM_047430866.1, XM_054333848.1
- RefSeq protein
- NP_001317439.1, NP_006338.1, XP_005270419.1, XP_047286822.1, XP_054189823.1
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
peptidylprolyl isomerase H
- Symbol
- PPIH
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:42,658,185-42,676,758
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PPIH PDB 1mzw.png
Show 9 more facts
- HomoloGene ID
- 38172
- chromosome
- human chromosome 1
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10465
- genomic start
- 42658335
- genomic end
- 111901091
- cytogenetic location
- 1p34.2
- expressed in
- lymph node
- Commons category
- Peptidyl-prolyl cis-trans isomerase H
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Peptidyl-prolyl cis-trans isomerase H is an enzyme that in humans is encoded by the PPIH gene.
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
Excerpted from Wikipedia’s “PPIH” article, available under the CC BY-SA 4.0 licence.