肾素-血管紧张素系统
Also known as Renin-angiotensin system, Renin-Angiotensin-Aldosterone System, renin-angiotensin system, renin–angiotensin–aldosterone system, RAAS, RAS
hormone system that is involved in the regulation of the plasma sodium concentration and arterial blood pressure
Research
42,134 papers- Calamari, Hyperkalemia, and Renin-Angiotensin System Blockade.Clinical journal of the American Society of Nephrology : CJASN · 2022
- ACE2 in the renin-angiotensin system.Clinical science (London, England : 1979) · 2020
- [Renin-angiotensin system].Nihon rinsho. Japanese journal of clinical medicine · 2010
- Cross-talk between exercises and renin-angiotensin-aldosterone-system blockade in hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
- Navigating Renin-Angiotensin System Inhibitors in Patients with Declines in eGFR.Journal of the American Society of Nephrology : JASN · 2024
via PubMed
Wikidata facts
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Article · 中文
肾素-血管張力素系统（英語：renin-angiotensin system，简称为RAS）或肾素-血管張力素-醛固酮系统（renin-angiotensin-aldosterone system, RAAS）是一个激素系統。當大量失血或血壓下降時，這個系統會被啟動，用以協助調節體內的長期血壓與細胞外液量（体液平衡）。 当血压降低时，肾脏分泌肾素。肾素催化水解产生。血管張力素I基本没有生物学活性，而是经（Angiotensin Converting Enzyme, ACE）剪切C-末端两个氨基酸残基而形成。血管張力素II具有高效的收缩血管作用，从而使血压升高；血管張力素II也能刺激肾上腺皮质分泌醛固酮。醛固酮能促进肾脏对水和钠离子的再吸收，继而增加体液容量，升高血压。
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