Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension. While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.
via PubMed
{{Drugbox | Verifiedfields = changed | verifiedrevid = 477317502 | IUPAC_name = (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide | image = Aliskiren.svg | image_class = skin-invert-image | width = 275
| tradename = Tekturna, Rasilez | Drugs.com = | MedlinePlus = a607039 | DailyMedID = Aliskiren | licence_EU = yes | licence_US = Tekturna | pregnancy_AU = | pregnancy_US = | pregnancy_category = C in first trimesterD in second and third trimesters | legal_AU = | legal_CA = | legal_UK = POM | legal_US = Rx-only | routes_of_administration = By mouth (tablets)
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).