rottlerin

Also known as mallotoxin, Kamalin, 3'-((8-cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl)-2',4',6'-trihydroxy-5'-methyl-acetophenone

Rottlerin (mallotoxin) is a polyphenol natural product isolated from the Asian tree Mallotus philippensis. Rottlerin displays a complex spectrum of pharmacology.

Wikidata facts

Mass: 516.178418

Show 3 more facts

chemical formula: C₃₀H₂₈O₈
isomeric SMILES: CC1=C(C(=C(C(=C1O)C(=O)C)O)CC2=C(C3=C(C(=C2O)C(=O)/C=C/C4=CC=CC=C4)OC(C=C3)(C)C)O)O
canonical SMILES: CC1=C(C(=C(C(=C1O)C(=O)C)O)CC2=C(C3=C(C(=C2O)C(=O)C=CC4=CC=CC=C4)OC(C=C3)(C)C)O)O

Sources (3)

via Wikidata · CC0

~5 min read

Article

10 sections

Contents

Effects
Uncoupler of oxidative phosphorylation
Potassium channel opener
Role in cardioplegia reperfusion
Contractility and vascular effects
Akt activation
Antioxidant properties
Ineffective PKCδ selective inhibitor
Sources
References

Rottlerin (mallotoxin) is a polyphenol natural product isolated from the Asian tree Mallotus philippensis. Rottlerin displays a complex spectrum of pharmacology.

== Effects ==