Structure via PubChem · Public domain (PubChem)
(RS)-ketoprofen
Sign in to saveAlso known as R.P. 19583, RP-19583, 3-benzoyl-alpha-methylbenzeneacetic acid, 3-benzoylhydratropic acid, 2-(3-benzoylphenyl)propionic acid, 3-benzoyl-α-methylbenzeneacetic acid, m-benzoylhydratropic acid, ketoprofen
Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin.
Chemical data
- Formula
- C16H14O3
- Molecular weight
- 254.28 g/mol
- IUPAC name
- 2-(3-benzoylphenyl)propanoic acid
- SMILES
- CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O
- InChIKey
- DKYWVDODHFEZIM-UHFFFAOYSA-N
- XLogP
- 3.1
- Polar surface area
- 54.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
5 papers- Quantum Insights into IR Spectral Density of Hydrogen-Bonded Cyclic Dimers: RS-Ibuprofen and RS-Ketoprofen as Model Systems.The journal of physical chemistry. A · 2026
- Effect of ketoprofen and its enantiomers on the renal disposition of methotrexate in the isolated perfused rat kidney.The Journal of pharmacy and pharmacology · 2003
- Plasma protein binding of ketoprofen enantiomers in man: method development and its application.Chirality · 1991
- The nature of hydrogen-bonding interactions in nonsteroidal anti-inflammatory drugs revealed by polarized IR spectroscopy.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2018
- Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract.Biochimica et biophysica acta · 2004
via PubMed
~6 min read
Encyclopedic overview
12 sectionsContents
- Medical uses
- Efficacy
- Adverse effects
- Mechanism
- Chirality and biological activity
- History
- Society and culture
- Brand names
- Veterinary medicine
- Ecological problems
- References
- External links
Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin.
It was patented in 1967 and approved for medical use in 1980.
Excerpted from Wikipedia’s “(RS)-ketoprofen” article, available under the CC BY-SA 4.0 licence.