RTN4

Also known as ASY, NI220/250, NOGO, NOGO-A, NOGOC, NSP, NSP-CL, Nbla00271

protein-coding gene in the species Homo sapiens

In the Vinony graph

Vinony's link graph records 17 inbound references to RTN4, and connects out to PubMed, Ensembl genome database project and protein.

It sits within the topics Enzyme inhibitors and Genes on human chromosome 2.

Vinony links it to 6 Wikipedia language editions.

Gene data

RTN4

Name: reticulon 4
Type: protein-coding
Position: 54,971,931–55,112,621 (−)
Aliases: ASY, NI220/250, NOGO, NOGOA, NOGOB, NSP, NSP-CL, Nbla00271, Nbla10545, RTN-X
Ensembl: ENSG00000115310
RefSeq RNA: NM_001321859.2, NM_001321860.1, NM_001321861.2, NM_001321862.2, NM_001321863.2
RefSeq protein: NP_001308788.1, NP_001308789.1, NP_001308790.1, NP_001308791.1, NP_001308792.1

This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].