(S)-(−)-colchicine
Sign in to saveColchicine is a medication used to prevent and treat gout, to treat familial Mediterranean fever and Behçet's disease, and to reduce the risk of myocardial infarction. The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the treatment of gout. Other uses for colchicine include the management of pericarditis.
Research
11,657 papers- Colchicine's Role in Cardiovascular Disease Management.Arteriosclerosis, thrombosis, and vascular biology · 2024
- Colchicine in Cardiovascular Disease: In-Depth Review.Circulation · 2022
- Colchicine's Long and Winding Road.Clinical therapeutics · 2023
- Colchicine--Update on mechanisms of action and therapeutic uses.Seminars in arthritis and rheumatism · 2015
- Colchicine poisoning: the dark side of an ancient drug.Clinical toxicology (Philadelphia, Pa.) · 2010
via PubMed
Article
25 sectionsContents
- Medical uses
- Gout
- Risk of cardiovascular disorders
- Other conditions
- Contraindications
- Adverse effects
- Toxicity
- Mechanism of toxicity
- Epidemiology
- Drug interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- History
- Sources and uses
- Physical properties
- Structure
- Light sensitivity
- Regulation
- Formulations and dosing
- Biosynthesis
- Purification
- Botanical use and seedless fruit
- References
- External links
Colchicine is a medication used to prevent and treat gout, to treat familial Mediterranean fever and Behçet's disease, and to reduce the risk of myocardial infarction. The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the treatment of gout. Other uses for colchicine include the management of pericarditis.
Colchicine is taken by mouth. The injectable route of administration for colchicine can be toxic. In 2008, the US Food and Drug Administration removed all injectable colchicine from the US market.
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Categories
5-HT3 receptor negative allosteric modulators5-HT3 receptor positive allosteric modulatorsAcetamidesAlkaloidsAntigout agentsBenzodihydroheptalenesDrugboxes which contain changes to watched fieldsDrugs developed by Takeda Pharmaceutical CompanyECHA InfoCard ID from WikidataGlycine receptor antagonistsMethoxy compoundsMicrotubule inhibitors