Structure via PubChem · Public domain (PubChem)
saxitoxin
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin. Ingestion of saxitoxin by humans, usually by consumption of shellfish contaminated by toxic algal blooms, is responsible for the illness known as paralytic shellfish poisoning (PSP).
Chemical data
- Formula
- C10H17N7O4
- Molecular weight
- 299.29 g/mol
- IUPAC name
- [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,8,9-tetrahydro-3H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
- SMILES
- C1CN2C(=N[C@H]([C@H]3[C@]2(C1(O)O)N=C(N3)N)COC(=O)N)N
- InChIKey
- RPQXVSUAYFXFJA-HGRQIUPRSA-N
- XLogP
- -4.6
- Polar surface area
- 185 Ų
- H-bond donors
- 6
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
2,197 papers~11 min read
Article
11 sectionsContents
- Source in nature
- Structure and synthesis
- Mechanism of action
- Biosynthesis
- Illness and poisoning
- Toxicology
- Illness in humans
- Military interest
- See also
- References
- External links
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin. Ingestion of saxitoxin by humans, usually by consumption of shellfish contaminated by toxic algal blooms, is responsible for the illness known as paralytic shellfish poisoning (PSP).
The term saxitoxin originates from the genus name of the butter clam (Saxidomus) from which it was first isolated. But the term saxitoxin can also refer to the entire suite of more than 50 structurally related neurotoxins (known collectively as "saxitoxins") produced by protists, algae and cyanobacteria which includes saxitoxin itself (STX), neosaxitoxin (NSTX), gonyautoxins (GTX) and decarbamoylsaxitoxin (dcSTX).