SCH-23390
Sign in to saveAlso known as SCH 23388, SCH23390, 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
SCH-23390, also known as halobenzazepine, is a synthetic compound that acts as a dopamine D1 receptor antagonist with either minimal or negligible effects on the D2 receptor.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 287.107692
Show 2 more facts
- chemical formula
- C₁₇H₁₈ClNO
- canonical SMILES
- CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Cl
Sources (2)
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Encyclopedic overview
2 sectionsContents
- See also
- References
SCH-23390, also known as halobenzazepine, is a synthetic compound that acts as a dopamine D1 receptor antagonist with either minimal or negligible effects on the D2 receptor.
In a 1990 study in rats SCH-23390 offered significant protection from death in dextroamphetamine overdose, without providing protection from death by methamphetamine overdose. The compound provided significant protection from cocaine overdose in rats only at the lowest dose tested in the measurement series. This suggested that dextroamphetamine and methamphetamine at high (lethal) doses have different mechanisms of toxicity in rats.
Excerpted from Wikipedia’s “SCH-23390” article, available under the CC BY-SA 4.0 licence.