SERPINB8
Sign in to saveAlso known as CAP2, PI8, serpin family B member 8, PSS5, PI-8, HMSD, HSMD-v, C18orf53
Serpin B8 is a protein that in humans is encoded by the SERPINB8 gene.
Gene data
SERPINB8- Name
- serpin family B member 8
- Type
- protein-coding
- Position
- 63,970,029–64,019,779 (+)
- Aliases
- C18orf53, CAP2, PI-8, PI8, PSS5
- Ensembl
- ENSG00000166401
- RefSeq RNA
- NM_001031848.2, NM_001276490.2, NM_001348367.2, NM_001348368.2, NM_001348369.2
- RefSeq protein
- NP_001027018.1, NP_001263419.1, NP_001335296.1, NP_001335297.1, NP_001335298.1
The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis. [provided by RefSeq, Jan 2017].
Gene Ontology
Molecular function
via MyGene.info
Gene · Ensembl
serpin family B member 8
- Symbol
- SERPINB8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:63,970,029-64,019,965
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 74445
- exact match
- identifiers.org/ncbigene/5271
- genomic end
- 61672278
- genomic start
- 63970029
- cytogenetic location
- 18q22.1
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- See also
- References
- Further reading
- External links
Serpin B8 is a protein that in humans is encoded by the SERPINB8 gene.
==See also== Serpin