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GeneQ18042522· pop 6· linked from 4 articles

SLAMF8

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Also known as BLAME, CD353, SBBI42, SLAM family member 8

SLAM family member 8 is a protein that in humans is encoded by the SLAMF8 gene.

Gene data

SLAMF8

Name: SLAM family member 8
Type: protein-coding
Position: 159,826,693–159,837,492 (+)
Aliases: BLAME, CD353, SBBI42
Ensembl: ENSG00000158714
RefSeq RNA: NM_001330741.2, NM_020125.3, XM_005245345.4, XM_011509775.3, XM_011509776.3
RefSeq protein: NP_001317670.1, NP_064510.1, XP_005245402.1, XP_011508077.1, XP_011508078.1

This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

leukocyte chemotaxis involved in inflammatory response B-1 B cell lineage commitment immune response negative regulation of macrophage chemotaxis defense response to bacterium regulation of B cell differentiation negative regulation of respiratory burst involved in inflammatory response negative regulation of monocyte chemotaxis

Molecular function

protein binding signaling receptor activity signaling receptor activity identical protein binding

Cellular component

cell surface membrane

via MyGene.info

Wikidata facts

Show 5 more facts

HomoloGene ID: 10589
exact match: identifiers.org/ncbigene/56833
genomic end: 159837492
genomic start: 159826811
cytogenetic location: 1q23.2

Sources (4)

via Wikidata · CC0

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Article

3 sections

Contents

Function
References
Further reading

SLAM family member 8 is a protein that in humans is encoded by the SLAMF8 gene.

== Function ==

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via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 1