KIF18A

Also known as MS-KIF18A, PPP1R99, kinesin family member 18A

Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor proteins.

Gene data

KIF18A

Name: kinesin family member 18A
Type: protein-coding
Position: 28,020,618–28,108,183 (−)
Aliases: MS-KIF18A, PPP1R99
Ensembl: ENSG00000121621
RefSeq RNA: NM_031217.4, XM_017018379.2, XM_017018380.2, XM_054370093.1, XM_054370094.1
RefSeq protein: NP_112494.3, XP_016873868.1, XP_016873869.1, XP_054226068.1, XP_054226069.1

KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied by OMIM, Aug 2008].

Pathways

Hemostasis Hemostasis Adaptive Immune System Amplification of signal from the kinetochores Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Signal Transduction Cell Cycle Immune System Signaling by Rho GTPases RHO GTPase Effectors

via MyGene.info

Gene · Ensembl

kinesin family member 18A

Symbol: KIF18A
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:28,020,618-28,108,186
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: KIF18A.png

Show 5 more facts

HomoloGene ID: 41820
exact match: identifiers.org/ncbigene/81930
genomic end: 28108156
genomic start: 28020619
cytogenetic location: 11p14.1

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Article

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Contents

Function
Therapeutic Target
References
Further reading
External links

Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor proteins.

== Function == KIF18A is a plus-end directed motor protein, and migrates to the plus ends of the spindle during early mitosis. It first accumulates there during prophase and metaphase, and is depleted during anaphase.